Monashee Mountain will face 10 rivals in Sunday's Dubai Poule d'Essai des Poulains (French 2000 Guineas) at Longchamp.
The unbeaten colt, trained by Aidan O'Brien, is the sole runner from Ballydoyle with stablemates Giant's Causeway, Bashkir, Manhattan and Royal Kingdom among the six overnight withdrawals.
Michael Kinane takes the ride on the son of Danzig.
Fanaar (Jeremy Noseda), Ekraar (Marcus Tregoning), Valentino (John Gosden) and Godolphin's Bachir all stand their ground and will be ridden by Jason Weaver, Richard Hills, Gerald Mosse and Frankie Dettori respectively.
Blu Air Force (Olivier Peslier), the crack Italian colt, rounds out the overseas sextet.
The home contingent includes the first three home in main trial race, the Prix de Fontainebleau, Berine's Son, Premier Pas and Slipstream King.
Godolphin's Glad Master and French-trained Firyal Pursuit were the other withdrawals.
Godolphin have withdrawn Teggiano and Dignify from the Dubai Poule d'Essai des Pouliches (French 1000 Guineas) on the same card, for which 11 horses have been declared.
Godolphin later announced that Teggiano was found to be lame this morning - forcing her withdrawal.
The filly will now be aimed at the Vodafone Oaks at Epsom on June 9th.
The Clive Brittain-trained Crimplene, winner of the German 1000 Guineas, will also miss the Group One prize, along with Kalypso Katie (Jeremy Noseda) and the Aidan O'Brien duo Alluring and Warrior Queen.
This leaves the John Dunlop-trained Dubai Duty Free Stakes winner Iftiraas (Pat Eddery) and Ben Hanbury's supplemented Alshakr (Richard Hills) as the only British runners.
Lady Of Chad, winner of the Prix Marcel Boussac last season, spearheads the home defence. She will have the help of a pacemaker, Saone Et Loire.
Foreign interest in the Group One Prix Lupin hinges around O'Brien's Ciro (Kinane) and Godolphin's River's Curtain (Dettori).
O'Brien's Bach was the sole overnight defector.
Freddie Head's Kutub, the impressive winner of another French Derby prep race, the Prix Noailles, spearheads a strong home defence.
Godolphin's Sampower Star (Dettori), the David Arbuthnot-trained Monkston Point (Richard Quinn) and the Richard Hannon-trained Watching (Richard Hughes) all tackle the Group Three Prix de Saint-Georges over five furlongs on the same card.
